Clinical Research

The Team

Jean-Christophe Corvol

Clinical Research Manager

Louise-Laure Mariani

Head of NEUROTRIALS & Medical Lead

The Missions

Clinical research at ICM is accelerated a premium clinical CRO, NEUROTRIALS®, which offers operational excellence at industry standards for investigational Phase 1b/2a trials

Clinical Research is one of the major activities of the ICM, using the latest cutting-edge genetic, biochemical, neuropsychology and neuroimaging technology available to study neurological diseases in observational studies, and in interventional studies.

Clinical trials are managed by the Clinical Investigation Center in Neurosciences (CIC Neurosciences) or by NEUROTRIALS, a "One shop CRO" phase IIa clinical studies in CNS: End To End process – from Concept Sheet / Study Synopsis to Clinical Study Report - with operational excellence.

The CIC Neurosciences consists in a full pipeline of clinical research facilities dedicated to neuroscience, from bench to bedside.

It is located in two different areas within Pitié-Salpêtrière hospital: the Brain and Spine Institute (ICM) building, and Paul Castaigne neurological department.

The investigated areas include Amyotrophic lateral sclerosis, Parkinson’s disease and Movement disorders, Huntington’s disease, Alzheimer’s and Prion diseases, Multiple sclerosis, Neuro-oncology, Epilepsy, Autism, Depression, Frontotemporal Lobar degenerations, Tourette syndrome, Sleep disorders.

It’s role is :

  • To organize a unique entry for clinical trials for investigators at Brain and Spine Institute (ICM) and the center for neurological diseases (Pôle MSN); 
  • Coordinate clinical research trials in neuroscience: proof-of-concept, phase II, phase III, cohort and translational studies; 
  • Provide the amenities to ensure high quality and ethics in clinical trials, and safety of volunteers participating in trials.

CIC NeuroScience assets :

  • more than 70 ongoing trials in neuroscience, 
  • more than 2000 visits per year,
  • 1200sqm for clinical research
  • 17 outpatients sits
  • 10 inpatients beds