The Team

Dr Louise-Laure MARIANI

Head of NEUROTRIALS & Medical Lead

The Missions

NEUROTRIALS is a "One shop CRO" phase IIa clinical studies in CNS: End To End process – from Concept Sheet / Study Synopsis to Clinical Study Report - with operational excellence

NEUROTRIALS is the only CRO in Europe specialized in phase IIa clinical studies in CNS - Proof of Confidence clinical trials, both for Investigational drugs and medical devices.

It offers operational excellence in running / delivering phase IIa clinical studies in CNS, in addition to access to academic, scientific and medical excellence of the Brain and Spine Institute (ICM).

NEUROTRIALSworks closely with the Clinical Investigation Center in Neurosciences (CIC Neurosciences) of the Pitié-Salpêtrière hospital (over 70 ongoing trials in neuroscience, over 2000 visits per year).

The main investigated areas are Amyotrophic lateral sclerosis, Parkinson’s disease and Movement disorders, Huntington’s disease, Alzheimer’s and Prion diseases, Multiple sclerosis, Neuro-oncology, Epilepsy, Autism, Depression, Frontotemporal Lobar degenerations, Tourette syndrome, Sleep disorders.


  • Operate with efficiency, agility and reactivity due to a lean organizational structure.
  • Deliver highly specific, innovative, informative, tailor-made data with high quality on industry standards.
  • Contribute to de-risk potential phase IIb and phase III studies for sponsors, early in the drug development process.
  • Contribute to the understanding of the MOA / pharmacology / first signs of efficacy of investigational drugs, on relatively short studies.
  • Direct Recruitment and follow up of patients as the Centre of Clinical Investigation (CIC) is located within the ICM, and in neurology / psychiatry units of the Pitié-Salpétrière hospital.


"One shop CRO": End To End process – from Concept Sheet / Study Synopsis to Clinical Study Report - with operational excellence

  • Full Project Management
  • Medical Writing
  • Study set up including submissions
  • Clinical Monitoring
  • Pharmacovigilance
  • Data Management & Biostatistics
  • Fast enrollment due to significant pool of patients on site at the hospital Pitié-Salpêtrière (biggest hospital in Europe in this field)
  • High patient retention rate and dedicated staff highly trained on clinical research

To know more

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